PTCE Top 200 · #117

Progesterone

Prometrium

Progesterone is the generic name for the brand-name drug Prometrium. It is a progestin (progesterone) used to treat HRT, amenorrhea. On the PTCE Top 200 drug list, Progesterone ranks #117 and is one of the most frequently tested hormones/women's health medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameProgesterone
Brand name(s)Prometrium
Drug classProgestin (progesterone)
Class groupHormones/Women's Health
Common useHRT, amenorrhea
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Progesterone used for?

Progestin hormone used with estrogen in hormone therapy to reduce endometrial hyperplasia risk; also used for certain menstrual disorders and as progesterone support in select settings depending on formulation.

What drug class is Progesterone?

Progesterone is a Progestin (progesterone) in the Hormones/Women's Health group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Progesterone

Major interactions

Is Progesterone a controlled substance?

No. Progesterone is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Progesterone (PTCE mnemonic)

PRO-metrium PROtects the endometrium — progesterone given with estrogen prevents endometrial hyperplasia. Bedtime dose (drowsy/dizzy); peanut oil capsule (allergy alert).
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PTCE exam tip

Progesterone is given WITH estrogen in HRT to protect the uterine lining — and Prometrium capsules famously contain peanut oil, an allergy screening point.

Progesterone FAQ

What is the brand name for Progesterone?

The brand name for Progesterone is Prometrium.

What is Progesterone used for?

Progesterone is used to treat HRT, amenorrhea. Progestin hormone used with estrogen in hormone therapy to reduce endometrial hyperplasia risk; also used for certain menstrual disorders and as progesterone support in select settings depending on formulation.

What drug class is Progesterone?

Progesterone is a Progestin (progesterone) (Hormones/Women's Health group).

Is Progesterone a controlled substance?

No. Progesterone is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Hormones/Women's Health group

Drill Progesterone the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).