PTCE Top 200 · #97

Ethinyl Estradiol / Norgestimate

Ortho Tri-Cyclen / Sprintec

Ethinyl Estradiol / Norgestimate is the generic name for the brand-name drug Ortho Tri-Cyclen. It is a combined oral contraceptive used to treat birth control, acne. On the PTCE Top 200 drug list, Ethinyl Estradiol / Norgestimate ranks #97 and is one of the most frequently tested hormones/women's health medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameEthinyl Estradiol / Norgestimate
Brand name(s)Ortho Tri-Cyclen / Sprintec
Drug classCombined oral contraceptive
Class groupHormones/Women's Health
Common usebirth control, acne
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Ethinyl Estradiol / Norgestimate used for?

Combined oral contraceptive used to prevent pregnancy; some products are also indicated for acne in appropriate patients.

What drug class is Ethinyl Estradiol / Norgestimate?

Ethinyl Estradiol / Norgestimate is a Combined oral contraceptive in the Hormones/Women's Health group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Ethinyl Estradiol / Norgestimate

Major interactions

Is Ethinyl Estradiol / Norgestimate a controlled substance?

No. Ethinyl Estradiol / Norgestimate is not a federally controlled substance (it is unscheduled by the DEA).

warning Boxed warning

WARNING: Cigarette smoking and serious cardiovascular events — contraindicated in women >35 years who smoke.

How to remember Ethinyl Estradiol / Norgestimate (PTCE mnemonic)

TRI-Cyclen cycles 3 progestin doses — EE + norgestimate combo OC. Acne benefit; clot risk (VTE/stroke); NO smoking >35yo (boxed).
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PTCE exam tip

Another combined oral contraceptive (estrogen + progestin). Recognizing 'ethinyl estradiol' as the estrogen component is the key exam skill.

Ethinyl Estradiol / Norgestimate FAQ

What is the brand name for Ethinyl Estradiol / Norgestimate?

The most common brand name for Ethinyl Estradiol / Norgestimate is Ortho Tri-Cyclen / Sprintec.

What is Ethinyl Estradiol / Norgestimate used for?

Ethinyl Estradiol / Norgestimate is used to treat birth control, acne. Combined oral contraceptive used to prevent pregnancy; some products are also indicated for acne in appropriate patients.

What drug class is Ethinyl Estradiol / Norgestimate?

Ethinyl Estradiol / Norgestimate is a Combined oral contraceptive (Hormones/Women's Health group).

Is Ethinyl Estradiol / Norgestimate a controlled substance?

No. Ethinyl Estradiol / Norgestimate is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Hormones/Women's Health group

Drill Ethinyl Estradiol / Norgestimate the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).