What is the brand name for Estradiol?
The brand name for Estradiol is Estrace.
PTCB TOP 200 · #56
Estradiol
Estrace
Estradiol is the generic name for the brand-name drug Estrace. It is an estrogen used to treat menopause symptoms. On the PTCE Top 200 drug list, Estradiol ranks #56 and is one of the most frequently tested hormones/women's health medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Estradiol |
|---|---|
| Brand name(s) | Estrace |
| Drug class | Estrogen |
| Class group | Hormones/Women's Health |
| Common use | menopause symptoms |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Estradiol used for?
• Moderate-to-severe vasomotor symptoms due to menopause. • Moderate-to-severe vulvar and vaginal atrophy due to menopause. • Hypoestrogenism due to hypogonadism, castration, or primary ovarian failure. • Prevention of postmenopausal osteoporosis (when appropriate).
What drug class is Estradiol?
Estradiol is an Estrogen in the Hormones/Women's Health group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Estradiol
- arrow_rightBreast tenderness
- arrow_rightNausea
- arrow_rightHeadache
- arrow_rightVaginal bleeding/spotting
- arrow_rightFluid retention
Major interactions
- arrow_rightEnzyme inducers (rifampin, carbamazepine, phenytoin) may ↓ estrogen levels/effect
- arrow_rightThyroid hormone replacement: estrogens may ↑ thyroid-binding globulin (dose adjustment may be needed)
- arrow_rightWarfarin/anticoagulants: may alter anticoagulant requirements
- arrow_rightOther drugs affecting CYP metabolism may change estradiol exposure (formulation-dependent)
Is Estradiol a controlled substance?
No. Estradiol is not a federally controlled substance (it is unscheduled by the DEA).
warning Boxed warning
Systemic estrogens: increased risk of endometrial cancer (with unopposed estrogen) and increased risk of cardiovascular events (MI, stroke, VTE) and probable dementia (in older postmenopausal women); use lowest effective dose for shortest duration.
How to remember Estradiol (PTCE mnemonic)
EStrace = ESTrogen — estradiol replaces. Clot risk (VTE/stroke), breast/endometrial cancer warning; lowest dose, shortest duration.
lightbulb
PTCE exam tip
Estradiol is an estrogen for menopause / HRT — it comes as oral, patch, and vaginal forms, and estrogens carry a clotting-risk warning.
Estradiol FAQ
What is Estradiol used for?
Estradiol is used to treat menopause symptoms. • Moderate-to-severe vasomotor symptoms due to menopause. • Moderate-to-severe vulvar and vaginal atrophy due to menopause. • Hypoestrogenism due to hypogonadism, castration, or primary ovarian failure. • Prevention of postmenopausal osteoporosis (when appropriate).
What drug class is Estradiol?
Estradiol is an Estrogen (Hormones/Women's Health group).
Is Estradiol a controlled substance?
No. Estradiol is not a federally controlled substance (it is unscheduled by the DEA).
Study guides that cover Estradiol
Free, in-depth guides to the patterns behind this drug — no app needed.
Drug suffix cheat sheetthe suffix that gives away this drug's class
How to memorize the Top 200 drugsa method for locking in brand↔generic pairs
LASA (look-alike/sound-alike) drugsthe name pairs most often mixed up
edit_noteSig codes cheat sheetthe abbreviations on this drug's labelSee all PTCE study guides or browse the full Top 200 drug list.
Drill Estradiol the way the PTCE asks it
RxReflex turns the Top 200 drugs into fast flashcard rounds, a guided Learn path, pharmacy math, and 40+ cheat sheets. Free to start.
Related drugs in the Hormones/Women's Health group
Last reviewed August 7, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).