PTCE Top 200 · #136

Norethindrone

Aygestin

Norethindrone is the generic name for the brand-name drug Aygestin. It is a progestin used to treat amenorrhea, endometriosis. On the PTCE Top 200 drug list, Norethindrone ranks #136 and is one of the most frequently tested hormones/women's health medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameNorethindrone
Brand name(s)Aygestin
Drug classProgestin
Class groupHormones/Women's Health
Common useamenorrhea, endometriosis
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Norethindrone used for?

Progestin used for secondary amenorrhea, abnormal uterine bleeding, and endometriosis (norethindrone acetate 5 mg). Note: the separate norethindrone 0.35 mg mini-pill is the progestin-only contraceptive, not this product.

What drug class is Norethindrone?

Norethindrone is a Progestin in the Hormones/Women's Health group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Norethindrone

Major interactions

Is Norethindrone a controlled substance?

No. Norethindrone is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Norethindrone (PTCE mnemonic)

AY-gestin = AGE-stops menses — NoreTHINdrone = 'thin lining'. Irregular bleeding common; for amenorrhea, endometriosis, abnormal uterine bleeding; clot risk.
lightbulb
PTCE exam tip

Norethindrone wears two hats: higher-dose Aygestin for gynecologic conditions vs progestin-only 'mini-pill' birth control — where same-time-every-day counseling defines the category.

Norethindrone FAQ

What is the brand name for Norethindrone?

The brand name for Norethindrone is Aygestin.

What is Norethindrone used for?

Norethindrone is used to treat amenorrhea, endometriosis. Progestin used for secondary amenorrhea, abnormal uterine bleeding, and endometriosis (norethindrone acetate 5 mg). Note: the separate norethindrone 0.35 mg mini-pill is the progestin-only contraceptive, not this product.

What drug class is Norethindrone?

Norethindrone is a Progestin (Hormones/Women's Health group).

Is Norethindrone a controlled substance?

No. Norethindrone is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Hormones/Women's Health group

Drill Norethindrone the way the PTCE asks it

RxReflex turns the Top 200 drugs into fast flashcard rounds, a guided Learn path, pharmacy math, and 40+ cheat sheets. Free to start.

Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).