What is the brand name for Ethinyl Estradiol / Levonorgestrel?
The most common brand name for Ethinyl Estradiol / Levonorgestrel is Seasonale / Aviane.
PTCE Top 200 · #138
Ethinyl Estradiol / Levonorgestrel
Seasonale / Aviane
Ethinyl Estradiol / Levonorgestrel is the generic name for the brand-name drug Seasonale. It is a combined oral contraceptive used to treat extended-cycle birth control. On the PTCE Top 200 drug list, Ethinyl Estradiol / Levonorgestrel ranks #138 and is one of the most frequently tested hormones/women's health medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Ethinyl Estradiol / Levonorgestrel |
|---|---|
| Brand name(s) | Seasonale / Aviane |
| Drug class | Combined oral contraceptive |
| Class group | Hormones/Women's Health |
| Common use | extended-cycle birth control |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Ethinyl Estradiol / Levonorgestrel used for?
Prevention of pregnancy (combined oral contraceptive).
What drug class is Ethinyl Estradiol / Levonorgestrel?
Ethinyl Estradiol / Levonorgestrel is a Combined oral contraceptive in the Hormones/Women's Health group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Ethinyl Estradiol / Levonorgestrel
- arrow_rightNausea
- arrow_rightBreast tenderness
- arrow_rightHeadache
- arrow_rightBreakthrough bleeding
- arrow_rightMood changes
Major interactions
- arrow_rightEnzyme inducers (rifampin, certain anticonvulsants, St. John's wort) → reduced contraceptive efficacy
- arrow_rightLamotrigine → decreased lamotrigine levels (seizure risk)
- arrow_rightHepatitis C regimens containing ombitasvir/paritaprevir/ritonavir/dasabuvir → ALT elevations (avoid per label)
Is Ethinyl Estradiol / Levonorgestrel a controlled substance?
No. Ethinyl Estradiol / Levonorgestrel is not a federally controlled substance (it is unscheduled by the DEA).
warning Boxed warning
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS. Smoking increases the risk of serious cardiovascular events from combined oral contraceptives; do not use in women >35 who smoke.
How to remember Ethinyl Estradiol / Levonorgestrel (PTCE mnemonic)
SEASONale = SEASONal periods (4/year, extended-cycle) — EE/levonorgestrel combo OC. Clot risk; NO smoking >35yo (boxed); breakthrough bleed at first.
lightbulb
PTCE exam tip
Extended-cycle pills mean just four scheduled periods a year — plus the combined-contraceptive constant: the smoking-over-35 clot-risk boxed warning.
Ethinyl Estradiol / Levonorgestrel FAQ
What is Ethinyl Estradiol / Levonorgestrel used for?
Ethinyl Estradiol / Levonorgestrel is used to treat extended-cycle birth control. Prevention of pregnancy (combined oral contraceptive).
What drug class is Ethinyl Estradiol / Levonorgestrel?
Ethinyl Estradiol / Levonorgestrel is a Combined oral contraceptive (Hormones/Women's Health group).
Is Ethinyl Estradiol / Levonorgestrel a controlled substance?
No. Ethinyl Estradiol / Levonorgestrel is not a federally controlled substance (it is unscheduled by the DEA).
Related drugs in the Hormones/Women's Health group
Drill Ethinyl Estradiol / Levonorgestrel the way the PTCE asks it
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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).