PTCE Top 200 · #169

Ofloxacin

Floxin

Ofloxacin is the generic name for the brand-name drug Floxin. It is a fluoroquinolone antibiotic used to treat bacterial infections. On the PTCE Top 200 drug list, Ofloxacin ranks #169 and is one of the most frequently tested infectious disease medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameOfloxacin
Brand name(s)Floxin
Drug classFluoroquinolone antibiotic
Class groupInfectious Disease
Common usebacterial infections
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Ofloxacin used for?

Treatment of susceptible bacterial infections (product-specific), such as respiratory, urinary tract, skin/soft tissue, and certain sexually transmitted infections.

What drug class is Ofloxacin?

Ofloxacin is a Fluoroquinolone antibiotic in the Infectious Disease group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Ofloxacin

Major interactions

Is Ofloxacin a controlled substance?

No. Ofloxacin is not a federally controlled substance (it is unscheduled by the DEA).

warning Boxed warning

Fluoroquinolone class boxed warning: risk of tendinitis/tendon rupture, peripheral neuropathy, and CNS effects; may worsen myasthenia gravis.

How to remember Ofloxacin (PTCE mnemonic)

FLOX-in = FLuoroquinOXIN — ofloxacin. Same boxed warnings as cipro: tendon rupture, neuropathy, CNS, aortic dissection; SEPARATE from Ca/Mg/Al/Fe (chelation); ↑QT.
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PTCE exam tip

Ofloxacin survives mostly as EAR and EYE drops — route-specific products of a fluoroquinolone that still carries the class tendon warning when taken orally.

Ofloxacin FAQ

What is the brand name for Ofloxacin?

The brand name for Ofloxacin is Floxin.

What is Ofloxacin used for?

Ofloxacin is used to treat bacterial infections. Treatment of susceptible bacterial infections (product-specific), such as respiratory, urinary tract, skin/soft tissue, and certain sexually transmitted infections.

What drug class is Ofloxacin?

Ofloxacin is a Fluoroquinolone antibiotic (Infectious Disease group).

Is Ofloxacin a controlled substance?

No. Ofloxacin is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Infectious Disease group

Drill Ofloxacin the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).