PTCE Top 200 · #103

Naproxen

Naprosyn

Naproxen is the generic name for the brand-name drug Naprosyn. It is a nsaid used to treat pain, inflammation. On the PTCE Top 200 drug list, Naproxen ranks #103 and is one of the most frequently tested pain/inflammation medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameNaproxen
Brand name(s)Naprosyn
Drug classNSAID
Class groupPain/Inflammation
Common usepain, inflammation
DEA scheduleUnscheduled
AvailabilityBoth prescription and OTC

What is Naproxen used for?

NSAID used to relieve pain and inflammation (e.g., arthritis, musculoskeletal pain, gout flares, tendinitis/bursitis) and for dysmenorrhea.

What drug class is Naproxen?

Naproxen is a NSAID in the Pain/Inflammation group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Naproxen

Major interactions

Is Naproxen a controlled substance?

No. Naproxen is not a federally controlled substance (it is unscheduled by the DEA).

warning Boxed warning

WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS — NSAIDs increase risk of MI/stroke and GI bleeding/ulcer/perforation.

How to remember Naproxen (PTCE mnemonic)

NAPRO-syn is the NAP-friendly NSAID — naproxen is BID (12-hr). Lowest CV risk among NSAIDs, highest GI risk; OTC at 220mg, max 1500mg/day.
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PTCE exam tip

Naproxen is the twice-daily NSAID (12-hour dosing, vs more frequent ibuprofen) — same GI-bleed and cardiovascular class warnings; OTC as Aleve.

Naproxen FAQ

What is the brand name for Naproxen?

The brand name for Naproxen is Naprosyn.

What is Naproxen used for?

Naproxen is used to treat pain, inflammation. NSAID used to relieve pain and inflammation (e.g., arthritis, musculoskeletal pain, gout flares, tendinitis/bursitis) and for dysmenorrhea.

What drug class is Naproxen?

Naproxen is a NSAID (Pain/Inflammation group).

Is Naproxen a controlled substance?

No. Naproxen is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Pain/Inflammation group

Drill Naproxen the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).