What is the brand name for Acetaminophen / Hydrocodone?
The most common brand name for Acetaminophen / Hydrocodone is Norco / Vicodin.
PTCB TOP 200 · #25
Acetaminophen / Hydrocodone
Norco / Vicodin
Acetaminophen / Hydrocodone is the generic name for the brand-name drug Norco. It is an opioid + acetaminophen combination used to treat moderate-severe pain. On the PTCE Top 200 drug list, Acetaminophen / Hydrocodone ranks #25 and is one of the most frequently tested pain/inflammation medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Acetaminophen / Hydrocodone |
|---|---|
| Brand name(s) | Norco / Vicodin |
| Drug class | Opioid + acetaminophen combination |
| Class group | Pain/Inflammation |
| Common use | moderate-severe pain |
| DEA schedule | C-II |
| Availability | Prescription only (Rx) |
What is Acetaminophen / Hydrocodone used for?
Opioid/acetaminophen combination for management of pain severe enough to require an opioid and when alternatives are inadequate.
What drug class is Acetaminophen / Hydrocodone?
Acetaminophen / Hydrocodone is an Opioid + acetaminophen combination in the Pain/Inflammation group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Acetaminophen / Hydrocodone
- arrow_rightConstipation
- arrow_rightDrowsiness
- arrow_rightNausea
- arrow_rightVomiting
- arrow_rightDizziness
Major interactions
- arrow_rightBenzodiazepines, alcohol, and other CNS depressants → profound sedation/respiratory depression
- arrow_rightCYP3A4 inhibitors/inducers may increase/decrease hydrocodone levels (overdose or withdrawal)
- arrow_rightOther acetaminophen‑containing products ↑ hepatotoxicity risk
- arrow_rightMAO inhibitors and serotonergic drugs can increase adverse reactions (use caution/avoid per label)
Is Acetaminophen / Hydrocodone a controlled substance?
Yes. Acetaminophen / Hydrocodone is a C-II controlled substance under federal law.
warning Boxed warning
BOXED WARNING: Risks of addiction, abuse, and misuse; life‑threatening respiratory depression; neonatal opioid withdrawal; and dangerous interactions with benzodiazepines/other CNS depressants. Also avoid exceeding total daily acetaminophen to prevent liver injury.
How to remember Acetaminophen / Hydrocodone (PTCE mnemonic)
NORCO = 'NO more pain' — hydrocodone (C-II opioid) + APAP. Constipation always, respiratory depression; APAP cap 4g/day → liver.
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PTCE exam tip
A Schedule II opioid combo — handle and count like other C-II controls. The acetaminophen component sets a hard daily ceiling, a common safety question.
Acetaminophen / Hydrocodone FAQ
What is Acetaminophen / Hydrocodone used for?
Acetaminophen / Hydrocodone is used to treat moderate-severe pain. Opioid/acetaminophen combination for management of pain severe enough to require an opioid and when alternatives are inadequate.
What drug class is Acetaminophen / Hydrocodone?
Acetaminophen / Hydrocodone is an Opioid + acetaminophen combination (Pain/Inflammation group).
Is Acetaminophen / Hydrocodone a controlled substance?
Yes. Acetaminophen / Hydrocodone is a C-II controlled substance under federal law.
Study guides that cover Acetaminophen / Hydrocodone
Free, in-depth guides to the patterns behind this drug — no app needed.
Controlled substance scheduleswhy this drug's schedule sets its refill limits
verified_userDEA numbers & DEA formsthe DEA paperwork controlled drugs require
e911_emergencyHigh-alert medications listthe meds where an error does the most harm
Drug suffix cheat sheetthe suffix that gives away this drug's classSee all PTCE study guides or browse the full Top 200 drug list.
Drill Acetaminophen / Hydrocodone the way the PTCE asks it
RxReflex turns the Top 200 drugs into fast flashcard rounds, a guided Learn path, pharmacy math, and 40+ cheat sheets. Free to start.
Related drugs in the Pain/Inflammation group
Last reviewed August 7, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).