PTCE Top 200 · #175

Fluconazole

Diflucan

Fluconazole is the generic name for the brand-name drug Diflucan. It is an azole antifungal used to treat fungal/yeast infections. On the PTCE Top 200 drug list, Fluconazole ranks #175 and is one of the most frequently tested infectious disease medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameFluconazole
Brand name(s)Diflucan
Drug classAzole antifungal
Class groupInfectious Disease
Common usefungal/yeast infections
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Fluconazole used for?

Treatment and prevention of susceptible fungal infections, including vaginal candidiasis, oropharyngeal/esophageal candidiasis, systemic candidiasis, cryptococcal meningitis, and others (product-specific).

What drug class is Fluconazole?

Fluconazole is an Azole antifungal in the Infectious Disease group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Fluconazole

Major interactions

Is Fluconazole a controlled substance?

No. Fluconazole is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Fluconazole (PTCE mnemonic)

DI-flucan DEfeats fungus — flu-CONAZOLE. Single 150mg for vaginal yeast; long T½; QT prolongation, hepatotoxicity, strong CYP2C9/3A4 inhibitor (↑warfarin, ↑sulfonylureas).
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PTCE exam tip

The famous SINGLE-dose treatment: one fluconazole 150 mg tablet for vaginal candidiasis — plus azole-class CYP interactions, classically spiking warfarin's INR.

Fluconazole FAQ

What is the brand name for Fluconazole?

The brand name for Fluconazole is Diflucan.

What is Fluconazole used for?

Fluconazole is used to treat fungal/yeast infections. Treatment and prevention of susceptible fungal infections, including vaginal candidiasis, oropharyngeal/esophageal candidiasis, systemic candidiasis, cryptococcal meningitis, and others (product-specific).

What drug class is Fluconazole?

Fluconazole is an Azole antifungal (Infectious Disease group).

Is Fluconazole a controlled substance?

No. Fluconazole is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Infectious Disease group

Drill Fluconazole the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).