PTCE Top 200 · #86

Cephalexin

Keflex

Cephalexin is the generic name for the brand-name drug Keflex. It is a cephalosporin antibiotic (1st gen) used to treat skin, UTI infections. On the PTCE Top 200 drug list, Cephalexin ranks #86 and is one of the most frequently tested infectious disease medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameCephalexin
Brand name(s)Keflex
Drug classCephalosporin antibiotic (1st gen)
Class groupInfectious Disease
Common useskin, UTI infections
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Cephalexin used for?

Cephalosporin antibiotic used for susceptible bacterial infections (e.g., skin/soft tissue, respiratory tract, urinary tract, and some bone infections).

What drug class is Cephalexin?

Cephalexin is a Cephalosporin antibiotic (1st gen) in the Infectious Disease group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Cephalexin

Major interactions

Is Cephalexin a controlled substance?

No. Cephalexin is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Cephalexin (PTCE mnemonic)

KEF-lex KILLs skin bugs — CEPHa-LEXin is 1st-gen cephalosporin (gram+ heavy). Skin/UTI; ~5% penicillin cross-reactivity; diarrhea, C. diff.
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PTCE exam tip

Cephalexin (Keflex) is a 1st-generation cephalosporin (the 'ceph- / cef-' stem) — note the possible cross-sensitivity in penicillin-allergic patients.

Cephalexin FAQ

What is the brand name for Cephalexin?

The brand name for Cephalexin is Keflex.

What is Cephalexin used for?

Cephalexin is used to treat skin, UTI infections. Cephalosporin antibiotic used for susceptible bacterial infections (e.g., skin/soft tissue, respiratory tract, urinary tract, and some bone infections).

What drug class is Cephalexin?

Cephalexin is a Cephalosporin antibiotic (1st gen) (Infectious Disease group).

Is Cephalexin a controlled substance?

No. Cephalexin is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Infectious Disease group

Drill Cephalexin the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).