PTCE Top 200 · #150

Acyclovir

Zovirax

Acyclovir is the generic name for the brand-name drug Zovirax. It is an antiviral (herpes) used to treat herpes (HSV, VZV). On the PTCE Top 200 drug list, Acyclovir ranks #150 and is one of the most frequently tested infectious disease medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameAcyclovir
Brand name(s)Zovirax
Drug classAntiviral (herpes)
Class groupInfectious Disease
Common useherpes (HSV, VZV)
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Acyclovir used for?

Treatment of herpes simplex virus (HSV) infections (e.g., genital herpes) and varicella-zoster virus (VZV) infections (e.g., shingles/chickenpox).

What drug class is Acyclovir?

Acyclovir is an Antiviral (herpes) in the Infectious Disease group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Acyclovir

Major interactions

Is Acyclovir a controlled substance?

No. Acyclovir is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Acyclovir (PTCE mnemonic)

ZO-virax ZAPs viruses — ACYclovir blocks viral DNA polymerase (HSV/VZV). Start at first sign; HYDRATE → crystalluria/AKI; renal dose-adjust; less bioavailable than valacyclovir.
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PTCE exam tip

Acyclovir treats — never cures — herpes outbreaks; its prodrug valacyclovir (Valtrex) doses less often, a favorite same-family comparison. Counsel hydration (kidney crystals).

Acyclovir FAQ

What is the brand name for Acyclovir?

The brand name for Acyclovir is Zovirax.

What is Acyclovir used for?

Acyclovir is used to treat herpes (HSV, VZV). Treatment of herpes simplex virus (HSV) infections (e.g., genital herpes) and varicella-zoster virus (VZV) infections (e.g., shingles/chickenpox).

What drug class is Acyclovir?

Acyclovir is an Antiviral (herpes) (Infectious Disease group).

Is Acyclovir a controlled substance?

No. Acyclovir is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Infectious Disease group

Drill Acyclovir the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).