PTCE Top 200 · #93

Acetaminophen / Oxycodone

Percocet

Acetaminophen / Oxycodone is the generic name for the brand-name drug Percocet. It is an opioid + acetaminophen combination used to treat moderate-severe pain. On the PTCE Top 200 drug list, Acetaminophen / Oxycodone ranks #93 and is one of the most frequently tested pain/inflammation medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameAcetaminophen / Oxycodone
Brand name(s)Percocet
Drug classOpioid + acetaminophen combination
Class groupPain/Inflammation
Common usemoderate-severe pain
DEA scheduleC-II
AvailabilityPrescription only (Rx)

What is Acetaminophen / Oxycodone used for?

Opioid + acetaminophen combination used for management of moderate to moderately severe pain when non‑opioid options are inadequate.

What drug class is Acetaminophen / Oxycodone?

Acetaminophen / Oxycodone is an Opioid + acetaminophen combination in the Pain/Inflammation group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Acetaminophen / Oxycodone

Major interactions

Is Acetaminophen / Oxycodone a controlled substance?

Yes. Acetaminophen / Oxycodone is a C-II controlled substance under federal law.

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WARNING: OPIOID RISKS — addiction/abuse/misuse; life‑threatening respiratory depression; neonatal opioid withdrawal; and risks from concomitant use with benzodiazepines/other CNS depressants.

How to remember Acetaminophen / Oxycodone (PTCE mnemonic)

PERCO-cet = 'PERilous COmbination' — oxycodone (C-II opioid) + APAP. Constipation always, respiratory depression; APAP cap 4g/day → hepatotoxicity.
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PTCE exam tip

Percocet = oxycodone + acetaminophen, a Schedule II combo. The acetaminophen sets a hard daily ceiling — a frequent safety/math question.

Acetaminophen / Oxycodone FAQ

What is the brand name for Acetaminophen / Oxycodone?

The brand name for Acetaminophen / Oxycodone is Percocet.

What is Acetaminophen / Oxycodone used for?

Acetaminophen / Oxycodone is used to treat moderate-severe pain. Opioid + acetaminophen combination used for management of moderate to moderately severe pain when non‑opioid options are inadequate.

What drug class is Acetaminophen / Oxycodone?

Acetaminophen / Oxycodone is an Opioid + acetaminophen combination (Pain/Inflammation group).

Is Acetaminophen / Oxycodone a controlled substance?

Yes. Acetaminophen / Oxycodone is a C-II controlled substance under federal law.

Related drugs in the Pain/Inflammation group

Drill Acetaminophen / Oxycodone the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).