PTCB DRUG CLASS
-sartan

ARBs

The no-cough alternative

Every generic name in this class ends in -sartan. High blood pressure and heart failure — often for patients who couldn't tolerate an ACE inhibitor.

Blocks the angiotensin II receptor itself, so the vessel-tightening signal never lands.

The 7 arbs in the PTCB Top 200

Generic Brand Common use
LosartanCozaarhypertension
Hydrochlorothiazide / LosartanHyzaarhypertension
ValsartanDiovanhypertension, HF
OlmesartanBenicarhypertension
IrbesartanAvaprohypertension
TelmisartanMicardishypertension
Sacubitril / ValsartanEntrestoheart failure (HFrEF)

Tap any generic name for its full drug guide — brand↔generic, side effects, interactions and the exam tip.

What to know for the exam

health_and_safety Safety

Contraindicated in pregnancy, exactly like ACE inhibitors — the two classes share that warning.

workspace_premium PTCE exam tip

-sartan is the ARB signal. ARBs and ACE inhibitors are not used together.

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Drill arbs the way the PTCE asks them

RxReflex groups the Top 200 drugs into classes like this one, then quizzes you on brand↔generic, class, side effects and interactions. Plus a guided Learn path, pharmacy math and 40+ cheat sheets. Free to start.

Frequently asked

What does the suffix -sartan mean? add

A generic drug name ending in -sartan identifies it as one of the arbs. High blood pressure and heart failure — often for patients who couldn't tolerate an ACE inhibitor.

What drugs are in the arbs class? add

Losartan, Hydrochlorothiazide / Losartan, Valsartan, Olmesartan, Irbesartan, Telmisartan, Sacubitril / Valsartan. All are in the PTCB Top 200.

What are arbs used for? add

High blood pressure and heart failure — often for patients who couldn't tolerate an ACE inhibitor.

How do arbs work? add

Blocks the angiotensin II receptor itself, so the vessel-tightening signal never lands.

Last reviewed August 7, 2026. For education only — not medical advice. Not affiliated with or endorsed by the PTCB.