PTCE Top 200 · #197

Tretinoin

Retin-A

Tretinoin is the generic name for the brand-name drug Retin-A. It is a topical retinoid used to treat acne, photoaging. On the PTCE Top 200 drug list, Tretinoin ranks #197 and is one of the most frequently tested dermatology medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameTretinoin
Brand name(s)Retin-A
Drug classTopical retinoid
Class groupDermatology
Common useacne, photoaging
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Tretinoin used for?

Topical treatment of acne vulgaris; also used for photoaging and other dermatologic conditions (product-specific).

What drug class is Tretinoin?

Tretinoin is a Topical retinoid in the Dermatology group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Tretinoin

Major interactions

Is Tretinoin a controlled substance?

No. Tretinoin is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Tretinoin (PTCE mnemonic)

RETIN-A RETrains skin — tretinoin (vitamin A acid) for acne/aging. APPLY AT NIGHT (UV-degraded); initial purge + dryness/redness; SUNSCREEN MANDATORY; avoid in pregnancy (topical tretinoin was category C; oral retinoids are X).
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PTCE exam tip

Tretinoin thins the skin's sun tolerance — apply at NIGHT with daytime sunscreen counseling — and never confuse topical tretinoin with oral isotretinoin and its iPLEDGE program.

Tretinoin FAQ

What is the brand name for Tretinoin?

The brand name for Tretinoin is Retin-A.

What is Tretinoin used for?

Tretinoin is used to treat acne, photoaging. Topical treatment of acne vulgaris; also used for photoaging and other dermatologic conditions (product-specific).

What drug class is Tretinoin?

Tretinoin is a Topical retinoid (Dermatology group).

Is Tretinoin a controlled substance?

No. Tretinoin is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Dermatology group

Drill Tretinoin the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).