What is the brand name for Sitagliptin?
The brand name for Sitagliptin is Januvia.
PTCE Top 200 · #123
Sitagliptin
Januvia
Sitagliptin is the generic name for the brand-name drug Januvia. It is a dpp-4 inhibitor used to treat type 2 diabetes. On the PTCE Top 200 drug list, Sitagliptin ranks #123 and is one of the most frequently tested endocrine/diabetes medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Sitagliptin |
|---|---|
| Brand name(s) | Januvia |
| Drug class | DPP-4 inhibitor |
| Class group | Endocrine/Diabetes |
| Common use | type 2 diabetes |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Sitagliptin used for?
Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus (alone or with other antidiabetic agents).
What drug class is Sitagliptin?
Sitagliptin is a DPP-4 inhibitor in the Endocrine/Diabetes group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Sitagliptin
- arrow_rightNasopharyngitis
- arrow_rightHeadache
- arrow_rightUpper respiratory infection
- arrow_rightDiarrhea
- arrow_rightNausea
Major interactions
- arrow_rightInsulin or sulfonylureas → increased risk of hypoglycemia (may need dose reduction)
- arrow_rightDigoxin: may increase digoxin levels—monitor if used together
Is Sitagliptin a controlled substance?
No. Sitagliptin is not a federally controlled substance (it is unscheduled by the DEA).
How to remember Sitagliptin (PTCE mnemonic)
JAN-uvia JUMPstarts incretins — sita-GLIPTIN blocks DPP-4 (keeps GLP-1 from 'slipping' away). Weight-neutral, low hypo risk; pancreatitis, joint pain, renal adjust.
lightbulb
PTCE exam tip
The suffix -gliptin = a DPP-4 inhibitor. Like metformin, sitagliptin rarely causes lows on its own — and Januvia vs Janumet (adds metformin) is the combo-product angle.
Sitagliptin FAQ
What is Sitagliptin used for?
Sitagliptin is used to treat type 2 diabetes. Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus (alone or with other antidiabetic agents).
What drug class is Sitagliptin?
Sitagliptin is a DPP-4 inhibitor (Endocrine/Diabetes group).
Is Sitagliptin a controlled substance?
No. Sitagliptin is not a federally controlled substance (it is unscheduled by the DEA).
Related drugs in the Endocrine/Diabetes group
Drill Sitagliptin the way the PTCE asks it
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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).