PTCE Top 200 · #145

Memantine

Namenda

Memantine is the generic name for the brand-name drug Namenda. It is a nmda receptor antagonist (dementia) used to treat moderate-severe dementia. On the PTCE Top 200 drug list, Memantine ranks #145 and is one of the most frequently tested cns/psych medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameMemantine
Brand name(s)Namenda
Drug classNMDA receptor antagonist (dementia)
Class groupCNS/Psych
Common usemoderate-severe dementia
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Memantine used for?

Treatment of moderate-to-severe dementia of the Alzheimer's type (NMDA receptor antagonist).

What drug class is Memantine?

Memantine is a NMDA receptor antagonist (dementia) in the CNS/Psych group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Memantine

Major interactions

Is Memantine a controlled substance?

No. Memantine is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Memantine (PTCE mnemonic)

NAM-enda NAMes things again — MEMantine is NMDA antagonist for moderate-severe dementia. 'Memory maintainer'; dizziness, confusion, constipation; renal dose-adjust.
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PTCE exam tip

Memantine's NMDA mechanism pairs with — not replaces — donepezil in moderate-to-severe dementia; the Namzaric combo makes ingredient-identification questions easy to write.

Memantine FAQ

What is the brand name for Memantine?

The brand name for Memantine is Namenda.

What is Memantine used for?

Memantine is used to treat moderate-severe dementia. Treatment of moderate-to-severe dementia of the Alzheimer's type (NMDA receptor antagonist).

What drug class is Memantine?

Memantine is a NMDA receptor antagonist (dementia) (CNS/Psych group).

Is Memantine a controlled substance?

No. Memantine is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the CNS/Psych group

Drill Memantine the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).