PTCE Top 200 · #76

Lisdexamfetamine

Vyvanse

Lisdexamfetamine is the generic name for the brand-name drug Vyvanse. It is a stimulant (adhd) used to treat ADHD, binge eating. On the PTCE Top 200 drug list, Lisdexamfetamine ranks #76 and is one of the most frequently tested cns/psych medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic name	Lisdexamfetamine
Brand name(s)	Vyvanse
Drug class	Stimulant (ADHD)
Class group	CNS/Psych
Common use	ADHD, binge eating
DEA schedule	C-II
Availability	Prescription only (Rx)

What is Lisdexamfetamine used for?

• Attention-deficit/hyperactivity disorder (ADHD). • Moderate-to-severe binge eating disorder in adults.

What drug class is Lisdexamfetamine?

Lisdexamfetamine is a Stimulant (ADHD) in the CNS/Psych group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Lisdexamfetamine

arrow_rightDecreased appetite/weight loss
arrow_rightInsomnia
arrow_rightDry mouth
arrow_rightIrritability/anxiety
arrow_rightIncreased heart rate/BP

Major interactions

arrow_rightMAO inhibitors (contraindicated) → hypertensive crisis risk
arrow_rightAcidifying/alkalinizing agents may alter amphetamine levels (urinary pH effect)
arrow_rightAntihypertensives may have reduced effect
arrow_rightOther sympathomimetics ↑ cardiovascular/CNS effects

Is Lisdexamfetamine a controlled substance?

Yes. Lisdexamfetamine is a C-II controlled substance under federal law.

warning Boxed warning

CNS stimulants/amphetamines have high potential for abuse and addiction; assess risk and monitor for abuse and dependence.

How to remember Lisdexamfetamine (PTCE mnemonic)

VY-vanse adVANces focus — lisdex-AMFETAMINE is C-II prodrug (activated in blood = lower abuse). ↓Appetite, ↓sleep, ↑BP/HR; AM dose only.

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PTCE exam tip

Lisdexamfetamine (Vyvanse) is a Schedule II ADHD prodrug — controlled-substance handling and no refills, like other amphetamines.