PTCE Top 200 · #59

Lamotrigine

Lamictal

Lamotrigine is the generic name for the brand-name drug Lamictal. It is an anticonvulsant / mood stabilizer used to treat seizures, bipolar. On the PTCE Top 200 drug list, Lamotrigine ranks #59 and is one of the most frequently tested cns/psych medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameLamotrigine
Brand name(s)Lamictal
Drug classAnticonvulsant / mood stabilizer
Class groupCNS/Psych
Common useseizures, bipolar
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Lamotrigine used for?

• Epilepsy: adjunct or monotherapy for focal seizures, primary generalized tonic-clonic seizures, and seizures of Lennox-Gastaut syndrome (age/indication varies). • Bipolar disorder: maintenance treatment to delay mood episodes (bipolar I).

What drug class is Lamotrigine?

Lamotrigine is an Anticonvulsant / mood stabilizer in the CNS/Psych group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Lamotrigine

Major interactions

Is Lamotrigine a controlled substance?

No. Lamotrigine is not a federally controlled substance (it is unscheduled by the DEA).

warning Boxed warning

Serious skin rashes (including Stevens-Johnson syndrome/TEN), sometimes fatal; risk increased with higher starting doses, rapid titration, and with valproate.

How to remember Lamotrigine (PTCE mnemonic)

LAM-ictal calms LAMe seizures + mood — lamo-TRIGINE. SLOW titration → Stevens-Johnson rash (STOP at first rash); no weight gain.
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PTCE exam tip

Lamotrigine (Lamictal) needs slow dose titration because of a serious rash (Stevens-Johnson) risk — heavily tested. Watch the LASA pair Lamictal / Lamisil.

Lamotrigine FAQ

What is the brand name for Lamotrigine?

The brand name for Lamotrigine is Lamictal.

What is Lamotrigine used for?

Lamotrigine is used to treat seizures, bipolar. • Epilepsy: adjunct or monotherapy for focal seizures, primary generalized tonic-clonic seizures, and seizures of Lennox-Gastaut syndrome (age/indication varies). • Bipolar disorder: maintenance treatment to delay mood episodes (bipolar I).

What drug class is Lamotrigine?

Lamotrigine is an Anticonvulsant / mood stabilizer (CNS/Psych group).

Is Lamotrigine a controlled substance?

No. Lamotrigine is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the CNS/Psych group

Drill Lamotrigine the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).