PTCE Top 200 · #115

Hydrochlorothiazide / Triamterene

Dyazide / Maxzide

Hydrochlorothiazide / Triamterene is the generic name for the brand-name drug Dyazide. It is a thiazide + k-sparing diuretic used to treat hypertension, edema. On the PTCE Top 200 drug list, Hydrochlorothiazide / Triamterene ranks #115 and is one of the most frequently tested cardiovascular medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameHydrochlorothiazide / Triamterene
Brand name(s)Dyazide / Maxzide
Drug classThiazide + K-sparing diuretic
Class groupCardiovascular
Common usehypertension, edema
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Hydrochlorothiazide / Triamterene used for?

Combination diuretic used for hypertension and edema (thiazide + potassium‑sparing) to lower BP and reduce fluid while limiting potassium loss.

What drug class is Hydrochlorothiazide / Triamterene?

Hydrochlorothiazide / Triamterene is a Thiazide + K-sparing diuretic in the Cardiovascular group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Hydrochlorothiazide / Triamterene

Major interactions

Is Hydrochlorothiazide / Triamterene a controlled substance?

No. Hydrochlorothiazide / Triamterene is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Hydrochlorothiazide / Triamterene (PTCE mnemonic)

DY-azide pairs DIuretics — HCTZ (wastes K+) + triamterene (spares K+) = net K+ neutral. Still monitor K+ + renal; sulfa allergy from HCTZ.
lightbulb
PTCE exam tip

Dyazide pairs potassium-WASTING HCTZ with potassium-SPARING triamterene — identifying both components and the potassium logic is the exam point.

Hydrochlorothiazide / Triamterene FAQ

What is the brand name for Hydrochlorothiazide / Triamterene?

The most common brand name for Hydrochlorothiazide / Triamterene is Dyazide / Maxzide.

What is Hydrochlorothiazide / Triamterene used for?

Hydrochlorothiazide / Triamterene is used to treat hypertension, edema. Combination diuretic used for hypertension and edema (thiazide + potassium‑sparing) to lower BP and reduce fluid while limiting potassium loss.

What drug class is Hydrochlorothiazide / Triamterene?

Hydrochlorothiazide / Triamterene is a Thiazide + K-sparing diuretic (Cardiovascular group).

Is Hydrochlorothiazide / Triamterene a controlled substance?

No. Hydrochlorothiazide / Triamterene is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Cardiovascular group

Drill Hydrochlorothiazide / Triamterene the way the PTCE asks it

RxReflex turns the Top 200 drugs into fast flashcard rounds, a guided Learn path, pharmacy math, and 40+ cheat sheets. Free to start.

Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).