PTCE Top 200 · #109

Hydralazine

Apresoline

Hydralazine is the generic name for the brand-name drug Apresoline. It is a direct vasodilator used to treat hypertension, HF. On the PTCE Top 200 drug list, Hydralazine ranks #109 and is one of the most frequently tested cardiovascular medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameHydralazine
Brand name(s)Apresoline
Drug classDirect vasodilator
Class groupCardiovascular
Common usehypertension, HF
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Hydralazine used for?

Vasodilator used to treat hypertension; also used (with isosorbide dinitrate) for heart failure in selected patients.

What drug class is Hydralazine?

Hydralazine is a Direct vasodilator in the Cardiovascular group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Hydralazine

Major interactions

Is Hydralazine a controlled substance?

No. Hydralazine is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Hydralazine (PTCE mnemonic)

APRE-soline RElieves vessel tension — hydral-AZINE = direct arteriolar 'HYDRant'. Headache, reflex tachycardia, fluid retention; lupus-like syndrome with chronic use.
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PTCE exam tip

The classic LASA pair: hydrALAZINE (blood pressure) vs hydrOXYzine (itching/anxiety) — Tall Man lettering exists because of this exact mix-up.

Hydralazine FAQ

What is the brand name for Hydralazine?

The brand name for Hydralazine is Apresoline.

What is Hydralazine used for?

Hydralazine is used to treat hypertension, HF. Vasodilator used to treat hypertension; also used (with isosorbide dinitrate) for heart failure in selected patients.

What drug class is Hydralazine?

Hydralazine is a Direct vasodilator (Cardiovascular group).

Is Hydralazine a controlled substance?

No. Hydralazine is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Cardiovascular group

Drill Hydralazine the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).