PTCE Top 200 · #80

Glimepiride

Amaryl

Glimepiride is the generic name for the brand-name drug Amaryl. It is a sulfonylurea used to treat type 2 diabetes. On the PTCE Top 200 drug list, Glimepiride ranks #80 and is one of the most frequently tested endocrine/diabetes medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameGlimepiride
Brand name(s)Amaryl
Drug classSulfonylurea
Class groupEndocrine/Diabetes
Common usetype 2 diabetes
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Glimepiride used for?

• Type 2 diabetes mellitus: improve glycemic control as an adjunct to diet and exercise.

What drug class is Glimepiride?

Glimepiride is a Sulfonylurea in the Endocrine/Diabetes group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Glimepiride

Major interactions

Is Glimepiride a controlled substance?

No. Glimepiride is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Glimepiride (PTCE mnemonic)

AMARYL = 'A-merry-LOW' — gli-MEPIRIDE is a sulfonylurea (pushes insulin). HYPOglycemia (esp. elderly/renal), weight gain; sulfa allergy crossover.
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PTCE exam tip

Glimepiride is a sulfonylurea — like glipizide it can cause hypoglycemia (unlike metformin). Take it with breakfast.

Glimepiride FAQ

What is the brand name for Glimepiride?

The brand name for Glimepiride is Amaryl.

What is Glimepiride used for?

Glimepiride is used to treat type 2 diabetes. • Type 2 diabetes mellitus: improve glycemic control as an adjunct to diet and exercise.

What drug class is Glimepiride?

Glimepiride is a Sulfonylurea (Endocrine/Diabetes group).

Is Glimepiride a controlled substance?

No. Glimepiride is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Endocrine/Diabetes group

Drill Glimepiride the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).