What is the brand name for Evolocumab?
The brand name for Evolocumab is Repatha.
PTCE Top 200 · #188
Evolocumab
Repatha
Evolocumab is the generic name for the brand-name drug Repatha. It is a pcsk9 inhibitor used to treat high cholesterol (familial). On the PTCE Top 200 drug list, Evolocumab ranks #188 and is one of the most frequently tested cardiovascular medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Evolocumab |
|---|---|
| Brand name(s) | Repatha |
| Drug class | PCSK9 inhibitor |
| Class group | Cardiovascular |
| Common use | high cholesterol (familial) |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Evolocumab used for?
Lowering LDL-C as an adjunct to diet (e.g., familial hypercholesterolemia, established ASCVD) and reduction of cardiovascular risk in certain patients (product-specific).
What drug class is Evolocumab?
Evolocumab is a PCSK9 inhibitor in the Cardiovascular group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Evolocumab
- arrow_rightInjection site reactions
- arrow_rightNasopharyngitis
- arrow_rightUpper respiratory infection
- arrow_rightFlu-like symptoms
- arrow_rightBack pain
Major interactions
- arrow_rightNo clinically significant drug-drug interactions expected (monoclonal antibody; not CYP-metabolized)
Is Evolocumab a controlled substance?
No. Evolocumab is not a federally controlled substance (it is unscheduled by the DEA).
How to remember Evolocumab (PTCE mnemonic)
REPATHA REPaths LDL out — evolo-CUMAB blocks PCSK9 (→ more LDL receptors, lower LDL ~60%). SubQ q2wk or monthly; injection-site reactions; very expensive add-on to statin.
lightbulb
PTCE exam tip
Evolocumab is the injectable cholesterol biologic — a PCSK9 -mab given every 2–4 weeks and kept refrigerated — for patients statins alone can't get to goal.
Evolocumab FAQ
What is Evolocumab used for?
Evolocumab is used to treat high cholesterol (familial). Lowering LDL-C as an adjunct to diet (e.g., familial hypercholesterolemia, established ASCVD) and reduction of cardiovascular risk in certain patients (product-specific).
What drug class is Evolocumab?
Evolocumab is a PCSK9 inhibitor (Cardiovascular group).
Is Evolocumab a controlled substance?
No. Evolocumab is not a federally controlled substance (it is unscheduled by the DEA).
Related drugs in the Cardiovascular group
Drill Evolocumab the way the PTCE asks it
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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).