PTCE Top 200 · #106

Diltiazem

Cardizem

Diltiazem is the generic name for the brand-name drug Cardizem. It is a calcium channel blocker (non-dihydropyridine) used to treat afib, hypertension, angina. On the PTCE Top 200 drug list, Diltiazem ranks #106 and is one of the most frequently tested cardiovascular medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameDiltiazem
Brand name(s)Cardizem
Drug classCalcium channel blocker (non-dihydropyridine)
Class groupCardiovascular
Common useafib, hypertension, angina
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Diltiazem used for?

Non‑dihydropyridine calcium channel blocker used for hypertension and angina; also used for rate control in certain supraventricular tachyarrhythmias (depending on formulation).

What drug class is Diltiazem?

Diltiazem is a Calcium channel blocker (non-dihydropyridine) in the Cardiovascular group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Diltiazem

Major interactions

Is Diltiazem a controlled substance?

No. Diltiazem is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Diltiazem (PTCE mnemonic)

CARD-izem guards the CARDiac AV node — DILT-iazem is non-DHP CCB (heart-selective). Slows AV node (afib rate control); bradycardia, constipation, edema; NO with β-blocker (heart block).
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PTCE exam tip

Diltiazem is a NON-dihydropyridine CCB — it slows the heart (afib rate control), unlike the -dipine CCBs that mainly lower pressure. Cardizem CD vs SR release forms trip up order entry.

Diltiazem FAQ

What is the brand name for Diltiazem?

The brand name for Diltiazem is Cardizem.

What is Diltiazem used for?

Diltiazem is used to treat afib, hypertension, angina. Non‑dihydropyridine calcium channel blocker used for hypertension and angina; also used for rate control in certain supraventricular tachyarrhythmias (depending on formulation).

What drug class is Diltiazem?

Diltiazem is a Calcium channel blocker (non-dihydropyridine) (Cardiovascular group).

Is Diltiazem a controlled substance?

No. Diltiazem is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Cardiovascular group

Drill Diltiazem the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).