PTCE Top 200 · #189

Desvenlafaxine

Pristiq

Desvenlafaxine is the generic name for the brand-name drug Pristiq. It is a snri antidepressant used to treat depression. On the PTCE Top 200 drug list, Desvenlafaxine ranks #189 and is one of the most frequently tested cns/psych medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameDesvenlafaxine
Brand name(s)Pristiq
Drug classSNRI antidepressant
Class groupCNS/Psych
Common usedepression
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Desvenlafaxine used for?

Treatment of major depressive disorder (MDD).

What drug class is Desvenlafaxine?

Desvenlafaxine is a SNRI antidepressant in the CNS/Psych group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Desvenlafaxine

Major interactions

Is Desvenlafaxine a controlled substance?

No. Desvenlafaxine is not a federally controlled substance (it is unscheduled by the DEA).

warning Boxed warning

Suicidal thoughts and behaviors: antidepressants increase risk in children, adolescents, and young adults; monitor closely.

How to remember Desvenlafaxine (PTCE mnemonic)

PRIS-tiq PRIES open mood — DES-venlafaxine is the active metabolite of Effexor (no CYP2D6 conversion needed). ↑BP, brutal withdrawal (taper slowly), suicidality (boxed).
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PTCE exam tip

Another 'refined parent' drug: DESvenlafaxine is venlafaxine's active metabolite — recognize the des- prefix, and keep the SNRI taper-don't-stop counseling.

Desvenlafaxine FAQ

What is the brand name for Desvenlafaxine?

The brand name for Desvenlafaxine is Pristiq.

What is Desvenlafaxine used for?

Desvenlafaxine is used to treat depression. Treatment of major depressive disorder (MDD).

What drug class is Desvenlafaxine?

Desvenlafaxine is a SNRI antidepressant (CNS/Psych group).

Is Desvenlafaxine a controlled substance?

No. Desvenlafaxine is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the CNS/Psych group

Drill Desvenlafaxine the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).