PTCE Top 200 · #82

Clonidine

Catapres

Clonidine is the generic name for the brand-name drug Catapres. It is an alpha-2 agonist (central antihypertensive) used to treat hypertension, ADHD. On the PTCE Top 200 drug list, Clonidine ranks #82 and is one of the most frequently tested cardiovascular medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameClonidine
Brand name(s)Catapres
Drug classAlpha-2 agonist (central antihypertensive)
Class groupCardiovascular
Common usehypertension, ADHD
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Clonidine used for?

Central alpha‑2 agonist used to treat hypertension; certain extended‑release forms are also used for ADHD.

What drug class is Clonidine?

Clonidine is an Alpha-2 agonist (central antihypertensive) in the Cardiovascular group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Clonidine

Major interactions

Is Clonidine a controlled substance?

No. Clonidine is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Clonidine (PTCE mnemonic)

CATA-pres CALMs the SNS — CLONidine 'CLONEs down' sympathetic tone. Dry mouth, drowsy, hypotension; NEVER stop abruptly → rebound HTN crisis.
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PTCE exam tip

Clonidine is a central alpha-2 agonist for blood pressure (and ADHD) — never stop abruptly (rebound hypertension). LASA: clonidine vs clonazepam.

Clonidine FAQ

What is the brand name for Clonidine?

The brand name for Clonidine is Catapres.

What is Clonidine used for?

Clonidine is used to treat hypertension, ADHD. Central alpha‑2 agonist used to treat hypertension; certain extended‑release forms are also used for ADHD.

What drug class is Clonidine?

Clonidine is an Alpha-2 agonist (central antihypertensive) (Cardiovascular group).

Is Clonidine a controlled substance?

No. Clonidine is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the Cardiovascular group

Drill Clonidine the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).