What is the brand name for Chlorthalidone?
The most common brand name for Chlorthalidone is Hygroton / Thalitone.
PTCB TOP 200 · #124
Chlorthalidone
Hygroton / Thalitone
Chlorthalidone is the generic name for the brand-name drug Hygroton. It is a thiazide-like diuretic used to treat hypertension, edema. On the PTCE Top 200 drug list, Chlorthalidone ranks #124 and is one of the most frequently tested cardiovascular medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Chlorthalidone |
|---|---|
| Brand name(s) | Hygroton / Thalitone |
| Drug class | Thiazide-like diuretic |
| Class group | Cardiovascular |
| Common use | hypertension, edema |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Chlorthalidone used for?
Treatment of hypertension; management of edema due to heart failure, hepatic cirrhosis, renal dysfunction, or corticosteroid/estrogen therapy.
What drug class is Chlorthalidone?
Chlorthalidone is a Thiazide-like diuretic in the Cardiovascular group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Chlorthalidone
- arrow_rightHypokalemia
- arrow_rightHyponatremia
- arrow_rightDizziness
- arrow_rightPolyuria
- arrow_rightHyperuricemia (gout)
- arrow_rightHyperglycemia
Major interactions
- arrow_rightLithium → increased lithium levels/toxicity
- arrow_rightDigoxin (esp. with low K/Mg) → arrhythmia risk
- arrow_rightNSAIDs → reduced diuretic/antihypertensive effect, renal risk
- arrow_rightOther antihypertensives → additive hypotension
Is Chlorthalidone a controlled substance?
No. Chlorthalidone is not a federally controlled substance (it is unscheduled by the DEA).
How to remember Chlorthalidone (PTCE mnemonic)
CHLOR-thalidone has CHLORonger action — more potent + longer than HCTZ (T½ ~40hr). ↓K+, ↓Na+, ↑uric acid (gout), photosensitivity; sulfa allergy.
lightbulb
PTCE exam tip
Chlorthalidone is thiazide-LIKE — more potent and much longer-acting than HCTZ, with the same low-potassium watch.
Chlorthalidone FAQ
What is Chlorthalidone used for?
Chlorthalidone is used to treat hypertension, edema. Treatment of hypertension; management of edema due to heart failure, hepatic cirrhosis, renal dysfunction, or corticosteroid/estrogen therapy.
What drug class is Chlorthalidone?
Chlorthalidone is a Thiazide-like diuretic (Cardiovascular group).
Is Chlorthalidone a controlled substance?
No. Chlorthalidone is not a federally controlled substance (it is unscheduled by the DEA).
Study guides that cover Chlorthalidone
Free, in-depth guides to the patterns behind this drug — no app needed.
Drug suffix cheat sheetthe suffix that gives away this drug's class
How to memorize the Top 200 drugsa method for locking in brand↔generic pairs
How hard is the PTCE?what the pass rate really means
Failed the PTCB? The comeback planwhat to do if the first attempt failsSee all PTCE study guides or browse the full Top 200 drug list.
Drill Chlorthalidone the way the PTCE asks it
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Written and reviewed by the RxReflex Content Team. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).