What is the brand name for Bupropion?
The brand name for Bupropion is Wellbutrin.
PTCE Top 200 · #17
Bupropion
Wellbutrin
Bupropion is the generic name for the brand-name drug Wellbutrin. It is an antidepressant (ndri) used to treat depression, smoking cessation. On the PTCE Top 200 drug list, Bupropion ranks #17 and is one of the most frequently tested cns/psych medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Bupropion |
|---|---|
| Brand name(s) | Wellbutrin |
| Drug class | Antidepressant (NDRI) |
| Class group | CNS/Psych |
| Common use | depression, smoking cessation |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Bupropion used for?
Atypical antidepressant for major depressive disorder and seasonal affective disorder; some products are used for smoking cessation.
What drug class is Bupropion?
Bupropion is an Antidepressant (NDRI) in the CNS/Psych group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Bupropion
- arrow_rightDry mouth
- arrow_rightInsomnia
- arrow_rightHeadache
- arrow_rightNausea
- arrow_rightAgitation
Major interactions
- arrow_rightMAO inhibitors (contraindicated)
- arrow_rightDrugs that lower seizure threshold (e.g., antipsychotics, tramadol) ↑ seizure risk
- arrow_rightCYP2D6 substrates (bupropion inhibits CYP2D6) → ↑ levels of some antidepressants/antipsychotics/beta‑blockers
- arrow_rightAlcohol: may increase neuropsychiatric effects; avoid heavy use
Is Bupropion a controlled substance?
No. Bupropion is not a federally controlled substance (it is unscheduled by the DEA).
warning Boxed warning
BOXED WARNING: Antidepressants can increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults—monitor closely.
How to remember Bupropion (PTCE mnemonic)
WELLbutrin = WELL for mood + smoking quit — bupropion is an NDRI. No sexual SE/weight gain BUT seizure risk; avoid in eating disorders.
lightbulb
PTCE exam tip
Bupropion is an atypical antidepressant also sold as Zyban for smoking cessation — same drug, two brands, a frequent exam point.
Bupropion FAQ
What is Bupropion used for?
Bupropion is used to treat depression, smoking cessation. Atypical antidepressant for major depressive disorder and seasonal affective disorder; some products are used for smoking cessation.
What drug class is Bupropion?
Bupropion is an Antidepressant (NDRI) (CNS/Psych group).
Is Bupropion a controlled substance?
No. Bupropion is not a federally controlled substance (it is unscheduled by the DEA).
Related drugs in the CNS/Psych group
Drill Bupropion the way the PTCE asks it
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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).