What is the brand name for Baclofen?
The brand name for Baclofen is Lioresal.
PTCE Top 200 · #87
Baclofen
Lioresal
Baclofen is the generic name for the brand-name drug Lioresal. It is a skeletal muscle relaxant (gaba-b agonist) used to treat muscle spasticity. On the PTCE Top 200 drug list, Baclofen ranks #87 and is one of the most frequently tested cns/psych medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Baclofen |
|---|---|
| Brand name(s) | Lioresal |
| Drug class | Skeletal muscle relaxant (GABA-B agonist) |
| Class group | CNS/Psych |
| Common use | muscle spasticity |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Baclofen used for?
Antispastic agent used to treat spasticity (often from multiple sclerosis or spinal cord disease/injury).
What drug class is Baclofen?
Baclofen is a Skeletal muscle relaxant (GABA-B agonist) in the CNS/Psych group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Baclofen
- arrow_rightDrowsiness
- arrow_rightDizziness
- arrow_rightWeakness
- arrow_rightFatigue
- arrow_rightNausea
- arrow_rightConfusion
- arrow_rightHypotonia
Major interactions
- arrow_rightAlcohol/opioids/benzodiazepines and other CNS depressants ↑ sedation/respiratory depression risk
- arrow_rightAdditive hypotension with antihypertensives
- arrow_rightAbrupt withdrawal (especially high dose/intrathecal) can cause severe symptoms—taper
Is Baclofen a controlled substance?
No. Baclofen is not a federally controlled substance (it is unscheduled by the DEA).
How to remember Baclofen (PTCE mnemonic)
Lio-RES-al RESolves spasticity — baclo-FEN is a GABA-B agonist. Drowsy, weakness; NEVER stop abruptly (hallucinations, seizures, rhabdo).
lightbulb
PTCE exam tip
Baclofen is a muscle relaxant for spasticity — taper to stop, since abrupt withdrawal can cause seizures (a key counseling point).
Baclofen FAQ
What is Baclofen used for?
Baclofen is used to treat muscle spasticity. Antispastic agent used to treat spasticity (often from multiple sclerosis or spinal cord disease/injury).
What drug class is Baclofen?
Baclofen is a Skeletal muscle relaxant (GABA-B agonist) (CNS/Psych group).
Is Baclofen a controlled substance?
No. Baclofen is not a federally controlled substance (it is unscheduled by the DEA).
Related drugs in the CNS/Psych group
Drill Baclofen the way the PTCE asks it
RxReflex turns the Top 200 drugs into fast flashcard rounds, a guided Learn path, pharmacy math, and 40+ cheat sheets. Free to start.
Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).