PTCE Top 200 · #90

Amitriptyline

Elavil

Amitriptyline is the generic name for the brand-name drug Elavil. It is a tricyclic antidepressant (tca) used to treat depression, nerve pain. On the PTCE Top 200 drug list, Amitriptyline ranks #90 and is one of the most frequently tested cns/psych medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameAmitriptyline
Brand name(s)Elavil
Drug classTricyclic antidepressant (TCA)
Class groupCNS/Psych
Common usedepression, nerve pain
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Amitriptyline used for?

Tricyclic antidepressant used to treat depression; commonly used off‑label for neuropathic pain and migraine prevention at lower doses.

What drug class is Amitriptyline?

Amitriptyline is a Tricyclic antidepressant (TCA) in the CNS/Psych group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Amitriptyline

Major interactions

Is Amitriptyline a controlled substance?

No. Amitriptyline is not a federally controlled substance (it is unscheduled by the DEA).

warning Boxed warning

WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS — increased risk of suicidal thinking/behavior in children, adolescents, and young adults; monitor closely.

How to remember Amitriptyline (PTCE mnemonic)

EL-avil 'ELevates' mood the OLD way — amiTRIPtyline (TCA): 'TRIP' on anticholinergic (dry/blurry/constipated/urinary retention) + sleepy + QT/orthostasis; overdose lethal.
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PTCE exam tip

Amitriptyline is a tricyclic antidepressant — strong anticholinergic effects and dangerous in overdose; often used off-label for nerve pain or migraine.

Amitriptyline FAQ

What is the brand name for Amitriptyline?

The brand name for Amitriptyline is Elavil.

What is Amitriptyline used for?

Amitriptyline is used to treat depression, nerve pain. Tricyclic antidepressant used to treat depression; commonly used off‑label for neuropathic pain and migraine prevention at lower doses.

What drug class is Amitriptyline?

Amitriptyline is a Tricyclic antidepressant (TCA) (CNS/Psych group).

Is Amitriptyline a controlled substance?

No. Amitriptyline is not a federally controlled substance (it is unscheduled by the DEA).

Related drugs in the CNS/Psych group

Drill Amitriptyline the way the PTCE asks it

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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).