PTCE Top 200 · #113

Alendronate

Fosamax

Alendronate is the generic name for the brand-name drug Fosamax. It is a bisphosphonate used to treat osteoporosis. On the PTCE Top 200 drug list, Alendronate ranks #113 and is one of the most frequently tested bone/metabolic medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.

Generic nameAlendronate
Brand name(s)Fosamax
Drug classBisphosphonate
Class groupBone/Metabolic
Common useosteoporosis
DEA scheduleUnscheduled
AvailabilityPrescription only (Rx)

What is Alendronate used for?

Bisphosphonate used to treat and prevent osteoporosis; also used for Paget’s disease and glucocorticoid‑induced osteoporosis in appropriate patients.

What drug class is Alendronate?

Alendronate is a Bisphosphonate in the Bone/Metabolic group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.

Common side effects of Alendronate

Major interactions

Is Alendronate a controlled substance?

No. Alendronate is not a federally controlled substance (it is unscheduled by the DEA).

How to remember Alendronate (PTCE mnemonic)

FOS-amax FOStErs bones — alendronate is a bisphosphonate. 'A-LIE-down NO!': empty stomach, full glass water, UPRIGHT 30+ min; jaw osteonecrosis, atypical femur fx.
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PTCE exam tip

Alendronate's counseling ritual IS the exam question: empty stomach, a full glass of plain water, stay upright 30 minutes — usually once weekly.

Alendronate FAQ

What is the brand name for Alendronate?

The brand name for Alendronate is Fosamax.

What is Alendronate used for?

Alendronate is used to treat osteoporosis. Bisphosphonate used to treat and prevent osteoporosis; also used for Paget’s disease and glucocorticoid‑induced osteoporosis in appropriate patients.

What drug class is Alendronate?

Alendronate is a Bisphosphonate (Bone/Metabolic group).

Is Alendronate a controlled substance?

No. Alendronate is not a federally controlled substance (it is unscheduled by the DEA).

Drill Alendronate the way the PTCE asks it

RxReflex turns the Top 200 drugs into fast flashcard rounds, a guided Learn path, pharmacy math, and 40+ cheat sheets. Free to start.

Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).