Antifungals
The -azole family
Every generic name in this class ends in -azole. Fungal and yeast infections — thrush, vaginal yeast infections, and fungal skin and nail infections.
Damages the fungal cell membrane so the cell can't survive.
The 2 antifungals in the PTCB Top 200
| Generic | Brand | Common use |
|---|---|---|
| Ketoconazole | Nizoral | fungal infections |
| Fluconazole | Diflucan | fungal/yeast infections |
Tap any generic name for its full drug guide — brand↔generic, side effects, interactions and the exam tip.
What to know for the exam
- check_circleGeneric names end in -azole.
- check_circleFluconazole is often a single oral dose for a vaginal yeast infection.
- check_circleThese are significant interaction drugs — they raise levels of many other medications.
- check_circleLonger courses may include liver monitoring.
Azoles interact with statins, warfarin and several others by blocking the same liver enzymes. Check the full profile.
-azole covers antifungals and PPIs (-prazole). Read the whole ending, not just the last four letters.
Drill antifungals the way the PTCE asks them
RxReflex groups the Top 200 drugs into classes like this one, then quizzes you on brand↔generic, class, side effects and interactions. Plus a guided Learn path, pharmacy math and 40+ cheat sheets. Free to start.
Frequently asked
What does the suffix -azole mean? add
A generic drug name ending in -azole identifies it as one of the antifungals. Fungal and yeast infections — thrush, vaginal yeast infections, and fungal skin and nail infections.
What drugs are in the antifungals class? add
Ketoconazole, Fluconazole. All are in the PTCB Top 200.
What are antifungals used for? add
Fungal and yeast infections — thrush, vaginal yeast infections, and fungal skin and nail infections.
How do antifungals work? add
Damages the fungal cell membrane so the cell can't survive.
Last reviewed August 7, 2026. For education only — not medical advice. Not affiliated with or endorsed by the PTCB.