What is the brand name for Allopurinol?
The brand name for Allopurinol is Zyloprim.
PTCB TOP 200 · #45
Allopurinol
Zyloprim
Allopurinol is the generic name for the brand-name drug Zyloprim. It is a xanthine oxidase inhibitor (gout) used to treat chronic gout. On the PTCE Top 200 drug list, Allopurinol ranks #45 and is one of the most frequently tested metabolic/rheumatology medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Allopurinol |
|---|---|
| Brand name(s) | Zyloprim |
| Drug class | Xanthine oxidase inhibitor (gout) |
| Class group | Metabolic/Rheumatology |
| Common use | chronic gout |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Allopurinol used for?
• Gout: reduce serum urate levels and prevent gout flares (after initial prophylaxis considerations). • Management of hyperuricemia associated with chemotherapy or disorders with urate overproduction. • Recurrent kidney stones due to high uric acid.
What drug class is Allopurinol?
Allopurinol is a Xanthine oxidase inhibitor (gout) in the Metabolic/Rheumatology group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Allopurinol
- arrow_rightRash
- arrow_rightGI upset (nausea, diarrhea)
- arrow_rightDrowsiness
Major interactions
- arrow_rightAzathioprine or 6-mercaptopurine: major toxicity risk (requires large dose reduction/avoid)
- arrow_rightWarfarin: may ↑ anticoagulant effect
- arrow_rightThiazide diuretics may ↑ hypersensitivity risk and urate levels
- arrow_rightAmpicillin/amoxicillin may ↑ rash risk
Is Allopurinol a controlled substance?
No. Allopurinol is not a federally controlled substance (it is unscheduled by the DEA).
How to remember Allopurinol (PTCE mnemonic)
ALLO-purinol ALLOws less uric acid — XO inhibitor for chronic gout (NOT acute flares). STOP for rash → Stevens-Johnson; ↑warfarin/6-MP.
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PTCE exam tip
Allopurinol PREVENTS gout long-term — it does not treat an acute attack, and starting it during a flare can worsen it (a favorite exam trap).
Allopurinol FAQ
What is Allopurinol used for?
Allopurinol is used to treat chronic gout. • Gout: reduce serum urate levels and prevent gout flares (after initial prophylaxis considerations). • Management of hyperuricemia associated with chemotherapy or disorders with urate overproduction. • Recurrent kidney stones due to high uric acid.
What drug class is Allopurinol?
Allopurinol is a Xanthine oxidase inhibitor (gout) (Metabolic/Rheumatology group).
Is Allopurinol a controlled substance?
No. Allopurinol is not a federally controlled substance (it is unscheduled by the DEA).
Study guides that cover Allopurinol
Free, in-depth guides to the patterns behind this drug — no app needed.
Drug suffix cheat sheetthe suffix that gives away this drug's class
How to memorize the Top 200 drugsa method for locking in brand↔generic pairs
Pharmacy math cheat sheetthe five calculation types the PTCE asks
What changed on the 2026 PTCB examthe new domain weights for 2026See all PTCE study guides or browse the full Top 200 drug list.
Drill Allopurinol the way the PTCE asks it
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Last reviewed August 7, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).