What is the brand name for Allopurinol?
The brand name for Allopurinol is Zyloprim.
PTCE Top 200 · #45
Allopurinol
Zyloprim
Allopurinol is the generic name for the brand-name drug Zyloprim. It is a xanthine oxidase inhibitor (gout) used to treat chronic gout. On the PTCE Top 200 drug list, Allopurinol ranks #45 and is one of the most frequently tested metabolic/rheumatology medications — commonly quizzed on its brand–generic pair, drug class, and key side effects.
| Generic name | Allopurinol |
|---|---|
| Brand name(s) | Zyloprim |
| Drug class | Xanthine oxidase inhibitor (gout) |
| Class group | Metabolic/Rheumatology |
| Common use | chronic gout |
| DEA schedule | Unscheduled |
| Availability | Prescription only (Rx) |
What is Allopurinol used for?
• Gout: reduce serum urate levels and prevent gout flares (after initial prophylaxis considerations). • Management of hyperuricemia associated with chemotherapy or disorders with urate overproduction. • Recurrent kidney stones due to high uric acid.
What drug class is Allopurinol?
Allopurinol is a Xanthine oxidase inhibitor (gout) in the Metabolic/Rheumatology group. Knowing the class is the fastest way to predict its uses, side effects, and the brand↔generic pairs the PTCE tests.
Common side effects of Allopurinol
- arrow_rightRash
- arrow_rightGI upset (nausea, diarrhea)
- arrow_rightDrowsiness
Major interactions
- arrow_rightAzathioprine or 6-mercaptopurine: major toxicity risk (requires large dose reduction/avoid)
- arrow_rightWarfarin: may ↑ anticoagulant effect
- arrow_rightThiazide diuretics may ↑ hypersensitivity risk and urate levels
- arrow_rightAmpicillin/amoxicillin may ↑ rash risk
Is Allopurinol a controlled substance?
No. Allopurinol is not a federally controlled substance (it is unscheduled by the DEA).
How to remember Allopurinol (PTCE mnemonic)
ALLO-purinol ALLOws less uric acid — XO inhibitor for chronic gout (NOT acute flares). STOP for rash → Stevens-Johnson; ↑warfarin/6-MP.
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PTCE exam tip
Allopurinol PREVENTS gout long-term — it does not treat an acute attack, and starting it during a flare can worsen it (a favorite exam trap).
Allopurinol FAQ
What is Allopurinol used for?
Allopurinol is used to treat chronic gout. • Gout: reduce serum urate levels and prevent gout flares (after initial prophylaxis considerations). • Management of hyperuricemia associated with chemotherapy or disorders with urate overproduction. • Recurrent kidney stones due to high uric acid.
What drug class is Allopurinol?
Allopurinol is a Xanthine oxidase inhibitor (gout) (Metabolic/Rheumatology group).
Is Allopurinol a controlled substance?
No. Allopurinol is not a federally controlled substance (it is unscheduled by the DEA).
Drill Allopurinol the way the PTCE asks it
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Last reviewed June 25, 2026. Educational use only — not medical advice. Verify clinical specifics with your pharmacist or a current label source such as DailyMed. RxReflex is not affiliated with or endorsed by the Pharmacy Technician Certification Board (PTCB).