DMARDs & immunosuppressants
Calming an overactive immune system
Rheumatoid arthritis, lupus, psoriasis and other autoimmune conditions; also transplant rejection.
Damps down the immune activity that is attacking the body's own tissue.
The 4 dmards & immunosuppressants in the PTCB Top 200
| Generic | Brand | Common use |
|---|---|---|
| Methotrexate | Trexall | RA, psoriasis, cancer |
| Hydroxychloroquine | Plaquenil | RA, lupus, malaria |
| Adalimumab | Humira | RA, psoriasis, Crohn's |
| Cyclosporine | Restasis | chronic dry eye |
Tap any generic name for its full drug guide — brand↔generic, side effects, interactions and the exam tip.
What to know for the exam
- check_circleMethotrexate for arthritis is dosed ONCE WEEKLY, not daily.
- check_circleFolic acid is usually taken alongside methotrexate to reduce side effects.
- check_circleAdalimumab is a refrigerated injectable biologic.
- check_circleHydroxychloroquine requires periodic eye examinations.
Weekly methotrexate dispensed or taken as a daily dose is a well-documented fatal error. The frequency must be verified every time.
Methotrexate's once-weekly schedule is one of the most commonly tested error-prevention points on the exam.
Drill dmards & immunosuppressants the way the PTCE asks them
RxReflex groups the Top 200 drugs into classes like this one, then quizzes you on brand↔generic, class, side effects and interactions. Plus a guided Learn path, pharmacy math and 40+ cheat sheets. Free to start.
Frequently asked
What drugs are in the dmards & immunosuppressants class? add
Methotrexate, Hydroxychloroquine, Adalimumab, Cyclosporine. All are in the PTCB Top 200.
What are dmards & immunosuppressants used for? add
Rheumatoid arthritis, lupus, psoriasis and other autoimmune conditions; also transplant rejection.
How do dmards & immunosuppressants work? add
Damps down the immune activity that is attacking the body's own tissue.
Last reviewed August 7, 2026. For education only — not medical advice. Not affiliated with or endorsed by the PTCB.